Airola, M.V., Allen, W.J., Pulkoski-Gross, M.J., Obeid, L.M., Rizzo, R.C., Hannun, Y.A. “Structural basis for ceramide recognition and hydrolysis by human neutral ceramidase,” Structure 2015, 23(8):1482-91. Editor’s Featured Article

Highlighted in Cell Podcast, August 2015 & Research Highlight

Shamseddine, A.A., Airola, M.V., Hannun, Y.A. “Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes,” Adv. Biol. Regul. 2015, 57C:24-41. link to article

Airola, M.V., Tumolo, J.M., Snider, J., Hannun, Y.A. “Identification and biochemical characterization of an acid sphingomyelinase-like protein from the bacterial plant pathogen Ralstonia solanacearum that hydrolyzes ATP to AMP but not sphingomyelin to ceramide,” PLoS One 2014, 9(8):e105830. link to article

Airola, M.V., Hannun, Y.A. “Sphingolipid metabolism and neutral sphingomyelinases,” Handb. Exp. Pharmacol. 2013, (215):57-76. link to article

Airola, M.V., Sukomon, N., Samanta, D., Borbat, P.P., Freed, J.H., Watts, K.J., and Crane, B.R. “HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors,” PLoS Biology 2013, 11(2):e1001479. link to article

Highlighted in PLoS BiologueA Little Switch

Airola, M.V., Huh, D., Sukomon, N., Widom, J., Sircar, R., Borbat, P.P., Freed, J.H., Watts, K.J., Crane, B.R. “Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling,” J. Mol. Biol. 2013, 425(5):886-901. link to article

Airola, M. V., Watts, K. J., and Crane, B. R. “Identifying Divergent HAMP Domains and Poly-HAMP Chains,” J. Biol. Chem. 2010, 285(23): le7. link to article

Airola, M. V., Watts, K. J., Bilwes, A. M., and Crane, B. R. “Structure of Concatenated HAMP Domains Provides a Mechanism for Signal Transduction,” Structure 2010, 18(4): 436-448. Editor’s Featured Article

Airola, M.V., Du, J., Dawson, J.H., and Crane, B.R. “Heme Binding to the Mammalian Circadian Clock Protein Period 2 is Non-Specific,” Biochemistry 2010, 49(20): 4327-38. link to article

Sudhamsu, J., Kabir, M., Airola, M.V., Patel, B.A., Yeh, S.R., Rousseau, D.L., and Crane, B.R. “Co-Expression of Ferrochelatase Allows for Complete Heme Incorporation into Recombinant Proteins Produced in E. coli,” Protein Expr. Purif. 2010, 73(1): 78-82. link to article